1970 An idea was born in the minds of Professors Nicolae Simionescu and Maya Simionescu: a research centre for Cell Biology and Pathology should be created in Romania. They initiated this project while in USA at the invitation of Professor George Palade with whom they had a great collaboration for 10 years at the Rockefeller University and Yale University (1970 -1979).

1971 The first draft of the Institute for Cellular Biology and Pathology (ICBP) made by Professors Nicolae Simionescu and Maya Simionescu.

1974 A new building was constructed according to the design, structural and functional planning of Nicolae Simionescu and Maya Simionescu; they also obtained Fulbright fellowships for 12 young investigators to be trained in excellent laboratories in USA. Modern equipment was purchased.

1979 Official Inauguration of the Institute with a Romanian – American Workshop attended by the Nobel Prize Laureates Professors George Palade, Christian de Duve and Gunter Blobel, and by Professors Marilyn Farquhar, David Sabatini, and Werner Franke.

The Institute belonged to the Ministry of Education.
Beginning of specific projects in cell biology and pathology
For the next 15 years, Maya and Nicolae Simionescu have maintained the position of Visiting Professors at Yale University, New Haven and Columbia Universi ty, New York, USA being for three months annually involved in teaching and research. These associations have facilitated continuation of privileged links with USA Universities and outstanding specialists in the field, keeping an open bridge for scientific exchanges and avoid isolation, as well as to obtain fellowships for ICBP researchers. During these years, numerous young investigators from ICBP were trained in prestigious American Universities.

1981 All the Romanian research funds were cut.
First application for a 3-year competitive grant to the National Institute of Health (NIH)-USA was successful.

1982 Professor Nicolae Simionescu founded the Romanian Society for Cell Biology (450 members throughout the country).
First Annual Congress of the Romanian Society for Cell Biology

1983 The second application for a competitive grant from NIH-USA was successful.
Second Romanian-American Workshop on” Cell Biology of the Vessel Wall”.

1985 Third Romanian American Workshop on” Cellular and Molecular Events in Atherogenesis”.

1986 The third application for a competitive grant from NIH-USA was successful.

1989 Fourth Romanian American Workshop on “Pathobiochemistry of the Arterial Wall”

1990 ICBP was affiliated to the Romanian Academy.
ICBP became Member Institution of the UNESCO Global Network for Molecular and Cell Biology (UNESCO-MCBN).

1991 Two collaborative grants (for 3 years) with Prof. Samuel Silverstein and Prof. David Stern from Columbia University, New York, USA, obtained by competition from FIRCA-NIH-USA.
Therefore, between 1981-1993 the research program of ICBP was mainly supported by competitive grants from NIH-USA.

1993 Funds obtained for collaborations within the European Community.

1995 Professor Nicolae Simionescu left this world. In his memory, the Institute is named ICBP „Nicolae Simionescu”.
Professor Maya Simionescu became the director of the Institute.

1996 The Institute was reconfirmed as member Institution of the UNESCO-MCBN.

1997 Grant awarded by the Swiss National Science Foundation for a collaborative project.

1999 The Institute was selected Center of Excellence of the Romanian Academy.

2000 ICBP “Nicolae Simionescu” was selected by competition Center of Excellence of the European Community.
The Institute was selected Center of Excellence of the Ministry of Education and Research.

2002 International Workshop “Cardiovascular Dysfunction in Hyperlipidemia and Diabetes” held within the framework of Center of Excellence of the European Community.
Meeting of the COST Action B-17 of the European Community:” Insulin Resistance, Obesity and Diabetes Mellitus in the Elderly”.

2004 International Anniversary Workshop – 25 years of activity of the Institute: “Cell and Molecular Biology – a key to defeat global risk diseases”.

2005 Grant awarded by the European Community FP6 Specific Support Action:”Strengthening the European Research Area by Reinforcement of Romanian ResearchCompetency in Genomics and Proteomics of Major Global Risk Diseases: Atherosclerosis, Diabetes and its Complications”(SERA). Project Director: MayaSimionescu (950,000 Euro). Within the SERA Project (2005-2008), ICBP organized 14 international Symposia and Workshops, accommodated 113 visits of European and U.S.A. scientists to the Institute and 83 ICBP scientists attended international congresses and inter-laboratory exchanges
International Symposium “Combating Cardiovascular Diseases and Diabetes”
International Symposium “New Insights in Molecular Medicine”

2006 Inaugural Workshop of the “Cardio-Diabetology Research Reports and Training Unit” Combating Cardiovascular Diseases and Diabetes”.
The 2nd International Congress of Cellular and Molecular Biology held together with the 24th Annual Meeting of the Romanian Society for Cell Biology.
International Symposium „Recent advances in cardio-diabetology”.
International Symposium “Advances in Cell and Molecular Biology and Pathology”. International Symposium”Cell and Molecular Biology for the Benefit of Cardiovascular Disease”
International Symposium “Advances in gene regulation”
International Symposium “Molecular biomarkers of cardiovascular disease and diabetes”

2007 International Symposium “Advances in Gene Regulation”
International Symposium “Novel Trends in Cell and Molecular Biopathology”
International Symposium “Development of in vitro tests as an alternative to animal experiments”
International Symposium “Stem Cells as therapeutic alternative”
International workshop “Inflammation-dependent vascular remodeling in atherosclerosis”.
25th Anniversary of the Romanian Society for Cell Biology – International Workshop ” From basic Science to Therapeutic Applications”.

2008 International Symposium “Translational Research in Vascular Medicine”.
The international Workshop “The promise of stem cell therapy”.
International Biomedicine Exploratory Workshop: “Translation of basic research discoveries into therapeutic applications”
International Symposium From gene expression and protein activation to human diseases

2009 The 30th Anniversary Workshop “30 Years on Route from Cell Biology to Molecular Medicine”
International Symposium “Molecular andmetabolic dysfunction in diabetes” part of the COST – Action BM0602 “Adipose tissue: a key target for prevention of the metabolic syndrome”.
Grant awarded for the “CARDIOPRO” investment project in RDI infrastructure and related administrative capacity” Extension and modernization of the research infrastructure for increasing competitiveness in the field of cardiovascular diseases, diabetes and obesity”. Co-funding: European Regional Development Fund – SOP “Increase of economic competitiveness”, Priority Axis 2: RTDI for Competitiveness, Operation 2.2.1., Financing contract: 17/01.03.2009, Project Director: Maya Simionescu.

2010 2nd International Workshop „On Route from Stem Cell Biology to Clinical Applications for Cardiovascular Regeneration”
2nd International Congress and the 28th Annual Session of the Romanian Society for Cell Biology
International Biomedicine Exploratory Workshop: “Trends in Stem Cell biology and Embryological Research”

2011 3rd International Congress and the 29th Annual Session of Romanian Society for Cell Biology.

2012 ICBP at the 33rd Anniversary “33 Years on the Road from Cell Biology to Translational and Regenerative Medicine”;

Annual Workshop of the FP7 “RAMSES” project: Reinforcement of the Adult stem cell research area through Mobility and Scientific networking between Egypt, Romania and Germany. Project nr. 245691/2010-2013, Bucharest;
4th International Congress and the 30th Annual Session of Romanian Society for Cell Biology;
Workshop “Electron microscopy in Romania” organized together with “Victor Babes” Institute;
Official presentation of the newly created RDI infrastructure, as a result of the CARDIOPRO investment project.